Granulomatous Inflammation: This is a rare type of inflammation which is often characterized by granuloma formation. This type of inflammation, however, may be present in certain disease processes but granulomatous inflammation may have characteristics which may not be true of granulomas.

The common sites of granulomatous inflammation include the oral and oropharyngeal cavities. Granulomatous inflammation over these areas are also somewhat baffling because there can be several pathologies for this. Tuberculosis and tertiary syphilis are the leading causes for the development of oral granulomatous inflammation. This can also be triggered by autoimmune diseases, deep fungal infections and even allergic reactions.

Granulomatous inflammations are considered to be chronic in origin and oftentimes characterized by the clumping of nucleated giant cells, macrophages and epithelioid cells. This type of inflammation would also lead to possible tissue fibrosis and even necrosis. This can be managed using anti-inflammatory medications such as corticosteroids to help halt the ongoing inflammatory process.