Spleen Pain: Pain from the spleen isn’t a very common happening but may occasionally occur if the spleen: is injured, enlarged or ruptured. Severity of an illness of spleen may fluctuate, starting from minor to easily correctable, to crisis and a condition that is life-threatening. The spleen is an organ that is heart-sized that is situated in the left section of the abdomen. It is right beneath the ribs, and close to the organ of the stomach. Not very big... more »